Cocoa (Theobroma cacao) is a critical cash crop for millions of smallholder farmers in West Africa, where Cocoa Swollen Shoot Virus Disease (CSSVD) and anthracnose cause devastating yield losses. Automated disease detection from leaf images is essential for early intervention, yet deploying such systems in resource-constrained settings demands models that are small, fast, and require no internet connectivity. Existing edge-deployable plant disease systems rely on end-to-end deep learning without uncertainty quantification, while Bayesian methods for edge devices focus on hardware-level inference architectures rather than agricultural applications. We bridge this gap with TinyBayes, the first framework to combine a closed-form Bayesian classifier with a mobile-grade computer vision pipeline for crop disease detection. Our pipeline uses YOLOv8-Nano (5.9 MB) for lesion localisation, MobileNetV3-Small (3.5 MB) for feature extraction, and the Jacobi prior; a Bayesian method that provides a closed form non-iterative estimators via projection, for the classification. The Jacobi-DMR (Distributed Multinomial Regression) classifier adds only 13.5 KB to the pipeline, bringing the total model size within 9.5 MB, while achieving 78.7% accuracy on the Amini Cocoa Contamination Challenge dataset and enabling end-to-end CPU inference under 150 ms per image. We benchmark against seven classifiers including Random Forest, SVM, Ridge, Lasso, Elastic Net, XGBoost, and Jacobi-GP, and demonstrate that the Jacobi-DMR offers the best trade-off between accuracy, model size, and inference speed for edge deployment. We have proved the asymptotic equivalence and consistency, asymptotic normality and the bias correction of Jacobi-DMR. All data and codes are available here: https://github.com/shouvik-sardar/TinyBayes

Accurate disease detection is of paramount importance for effective medical treatment and patient care. However, the process of disease detection is often associated with extensive medical testing and considerable costs, making it impractical to perform all possible medical tests on a patient to diagnose or predict hundreds or thousands of diseases. In this work, we propose Collaborative Learning for Disease Detection (CLDD), a novel graph-based deep learning model that formulates disease detection as a collaborative learning task by exploiting associations among diseases and similarities among patients adaptively. CLDD integrates patient-disease interactions and demographic features from electronic health records to detect hundreds or thousands of diseases for every patient, with little to no reliance on the corresponding medical tests. Extensive experiments on a processed version of the MIMIC-IV dataset comprising 61,191 patients and 2,000 diseases demonstrate that CLDD consistently outperforms representative baselines across multiple metrics, achieving a 6.33\% improvement in recall and 7.63\% improvement in precision. Furthermore, case studies on individual patients illustrate that CLDD can successfully recover masked diseases within its top-ranked predictions, demonstrating both interpretability and reliability in disease prediction. By reducing diagnostic costs and improving accessibility, CLDD holds promise for large-scale disease screening and social health security.

Plant diseases pose a significant threat to global agriculture, causing over $220 billion in annual economic losses and jeopardizing food security. The timely and accurate detection of these diseases from plant leaf images is critical to mitigating their adverse effects. Deep neural network Ensembles (Deep Ensembles) have emerged as a powerful approach to enhancing prediction accuracy by leveraging the strengths of diverse Deep Neural Networks (DNNs). However, selecting high-performing ensemble member models is challenging due to the inherent difficulty in measuring ensemble diversity. In this paper, we introduce the Synergistic Diversity (SQ) framework to enhance plant disease detection accuracy. First, we conduct a comprehensive analysis of the limitations of existing ensemble diversity metrics (denoted as Q metrics), which often fail to identify optimal ensemble teams. Second, we present the SQ metric, a novel measure that captures the synergy between ensemble members and consistently aligns with ensemble accuracy. Third, we validate our SQ approach through extensive experiments on a plant leaf image dataset, which demonstrates that our SQ metric substantially improves ensemble selection and enhances detection accuracy. Our findings pave the way for a more reliable and efficient image-based plant disease detection.

Parkinson's disease (PD) is a progressive neurodegenerative disorder that, in addition to directly impairing functional mobility, is frequently associated with vocal impairments such as hypophonia and dysarthria, which typically manifest in the early stages. The use of vocal biomarkers to support the early diagnosis of PD presents a non-invasive, low-cost, and accessible alternative in clinical settings. Thus, the objective of this cross-sectional study was to consistently evaluate the effectiveness of a Deep Neural Network (DNN) in distinguishing individuals with Parkinson's disease from healthy controls, in comparison with traditional Machine Learning (ML) methods, using vocal biomarkers. Two publicly available voice datasets were used. Mel-frequency cepstral coefficients (MFCCs) were extracted from the samples, and model robustness was assessed using a validation strategy with 1000 independent random executions. Performance was evaluated using classification statistics. Since normality assumptions were not satisfied, non-parametric tests (Kruskal-Wallis and Bonferroni post-hoc tests) were applied to verify whether the tested classification models were similar or different in the classification of PD. With an average accuracy of $98.65\%$ and $92.11\%$ on the Italian Voice dataset and Parkinson's Telemonitoring dataset, respectively, the DNN demonstrated superior performance and efficiency compared to traditional ML models, while also achieving competitive results when benchmarked against relevant studies. Overall, this study confirms the efficiency of DNNs and emphasizes their potential to provide greater accuracy and reliability for the early detection of neurodegenerative diseases using voice-based biomarkers.

The coupling signal refers to a latent physiological signal that characterizes the transformation from cardiac electrical excitation, captured by the electrocardiogram (ECG), to mechanical contraction, recorded by the phonocardiogram (PCG). By encoding the temporal and functional interplay between electrophysiological and hemodynamic events, it serves as an intrinsic link between modalities and offers a unified representation of cardiac function, with strong potential to enhance multi-modal cardiovascular disease (CVD) detection. However, existing coupling signal estimation methods remain highly vulnerable to noise, particularly in real-world clinical and physiological settings, which undermines their robustness and limits practical value. In this study, we propose Noise-Robust Multi-Modal Coupling Signal Estimation (NMCSE), which reformulates coupling signal estimation as a distribution matching problem solved via optimal transport. By jointly aligning amplitude and timing, NMCSE avoids noise amplification and enables stable signal estimation. When integrated into a Temporal-Spatial Feature Extraction (TSFE) network, the estimated coupling signal effectively enhances multi-modal fusion for more accurate CVD detection. To evaluate robustness under real-world conditions, we design two complementary experiments targeting distinct sources of noise. The first uses the PhysioNet 2016 dataset with simulated hospital noise to assess the resilience of NMCSE to clinical interference. The second leverages the EPHNOGRAM dataset with motion-induced physiological noise to evaluate intra-state estimation stability across activity levels. Experimental results show that NMCSE consistently outperforms existing methods under both clinical and physiological noise, highlighting it as a noise-robust estimation approach that enables reliable multi-modal cardiac detection in real-world conditions.

Abstract--Alzheimer's disease is a severe brain disorder that causes harm in various brain areas and leads to memory damage. The limited availability of labeled medical data poses a significant challenge for accurate Alzheimer's disease detection. There is a critical need for effective methods to improve the accuracy of Alzheimer's disease detection, considering the scarcity of labeled data, the complexity of the disease, and the constraints related to data privacy. T o address this challenge, our study leverages the power of big data in the form of pre-trained Convolutional Neural Networks (CNNs) within the framework of Few-Shot Learning (FSL) and ensemble learning. We propose an ensemble approach based on a Prototypical Network (ProtoNet), a powerful method in FSL, integrating various pre-trained CNNs as encoders. This integration enhances the richness of features extracted from medical images. Our approach also includes a combination of class-aware loss and entropy loss to ensure a more precise classification of Alzheimer's disease progression levels. The effectiveness of our method was evaluated using two datasets, the Kaggle Alzheimer dataset, and the ADNI dataset, achieving an accuracy of 99.72% and 99.86%, respectively. The comparison of our results with relevant state-of-the-art studies demonstrated that our approach achieved superior accuracy and highlighted its validity and potential for real-world applications in early Alzheimer's disease detection. Index T erms--Few-shot learning, prototypical network, ensemble learning, transfer learning, pre-trained models, healthcare, Alzheimer disease. LZHEIMER'S disease is a progressive neurodegenera-tive disorder that mainly affects the elderly and causes memory loss and severe cognitive decline. The advances in medical imaging technologies, such as Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET), have opened new avenues for the analysis and understanding of this severe disease [1], [2]. Employing data analytics on these images helps to provide detailed insights about the structural and functional changes in the brain caused by this disease, which facilitates the early diagnosis and monitoring of disease progression [3]. However, the application of traditional Machine Learning (ML) techniques in analyzing medical images for Alzheimer's disease diagnosis faces significant challenges [4]. One of the primary limitations is the scarcity of labeled data.

With the global population increasing and arable land resources becoming increasingly limited, smart and precision agriculture have emerged as essential directions for sustainable agricultural development. Artificial intelligence (AI), particularly deep learning models, has been widely adopted in applications such as crop monitoring, pest detection, and yield prediction. Among recent generative models, diffusion models have demonstrated considerable potential in agricultural image processing, data augmentation, and remote sensing analysis. Compared to traditional generative adversarial networks (GANs), diffusion models exhibit greater training stability and superior image generation quality, effectively addressing challenges such as limited annotated datasets and imbalanced sample distributions in agricultural scenarios. This paper reviews recent advancements in the application of diffusion models within agriculture, focusing on their roles in crop disease and pest detection, remote sensing image enhancement, crop growth prediction, and agricultural resource management. Diffusion models have been found useful in improving tasks like image generation, denoising, and data augmentation in agriculture, especially when environmental noise or variability is present. While their high computational requirements and limited generalizability across domains remain concerns, the approach is gradually proving effective in real-world applications such as precision crop monitoring. As research progresses, these models may help support sustainable agriculture and address emerging challenges in food systems.

Rice is a staple food of global importance in terms of trade, nutrition, and economic growth. Among Asian nations such as China, India, Pakistan, Thailand, Vietnam and Indonesia are leading producers of both long and short grain varieties, including basmati, jasmine, arborio, ipsala, and kainat saila. To ensure consumer satisfaction and strengthen national reputations, monitoring rice crops and grain quality is essential. Manual inspection, however, is labour intensive, time consuming and error prone, highlighting the need for automated solutions for quality control and yield improvement. This study proposes an automated approach to classify five rice grain varieties using Convolutional Neural Networks (CNN). A publicly available dataset of 75000 images was used for training and testing. Model evaluation employed accuracy, recall, precision, F1-score, ROC curves, and confusion matrices. Results demonstrated high classification accuracy with minimal misclassifications, confirming the model effectiveness in distinguishing rice varieties. In addition, an accurate diagnostic method for rice leaf diseases such as Brown Spot, Blast, Bacterial Blight, and Tungro was developed. The framework combined explainable artificial intelligence (XAI) with deep learning models including CNN, VGG16, ResNet50, and MobileNetV2. Explainability techniques such as SHAP (SHapley Additive exPlanations) and LIME (Local Interpretable Model-agnostic Explanations) revealed how specific grain and leaf features influenced predictions, enhancing model transparency and reliability. The findings demonstrate the strong potential of deep learning in agricultural applications, paving the way for robust, interpretable systems that can support automated crop quality inspection and disease diagnosis, ultimately benefiting farmers, consumers, and the agricultural economy.

Despite progress in AI-based plant diagnostics, sugarcane farmers in low-resource regions remain vulnerable to leaf diseases due to the lack of scalable, efficient, and interpretable tools. Many deep learning models fail to generalize under real-world conditions and require substantial computational resources, limiting their use in resource-constrained regions. In this paper, we present SugarcaneLD-BD, a curated dataset for sugarcane leaf-disease classification; SugarcaneShuffleNet, an optimized lightweight model for rapid on-device diagnosis; and SugarcaneAI, a Progressive Web Application for field deployment. SugarcaneLD-BD contains 638 curated images across five classes, including four major sugarcane diseases, collected in Bangladesh under diverse field conditions and verified by expert pathologists. To enhance diversity, we combined SugarcaneLD-BD with two additional datasets, yielding a larger and more representative corpus. Our optimized model, SugarcaneShuffleNet, offers the best trade-off between speed and accuracy for real-time, on-device diagnosis. This 9.26 MB model achieved 98.02% accuracy, an F1-score of 0.98, and an average inference time of 4.14 ms per image. For comparison, we fine-tuned five other lightweight convolutional neural networks: MnasNet, EdgeNeXt, EfficientNet-Lite, MobileNet, and SqueezeNet via transfer learning and Bayesian optimization. MnasNet and EdgeNeXt achieved comparable accuracy to SugarcaneShuffleNet, but required significantly more parameters, memory, and computation, limiting their suitability for low-resource deployment. We integrate SugarcaneShuffleNet into SugarcaneAI, delivering Grad-CAM-based explanations in the field. Together, these contributions offer a diverse benchmark, efficient models for low-resource environments, and a practical tool for sugarcane disease classification. It spans varied lighting, backgrounds and devices used on-farm

Foundation models (FMs) have shown great promise in medical image analysis by improving generalization across diverse downstream tasks. In ophthalmology, several FMs have recently emerged, but there is still no clear answer to fundamental questions: Which FM performs the best? Are they equally good across different tasks? What if we combine all FMs together? To our knowledge, this is the first study to systematically evaluate both single and fused ophthalmic FMs. To address these questions, we propose FusionFM, a comprehensive evaluation suite, along with two fusion approaches to integrate different ophthalmic FMs. Our framework covers both ophthalmic disease detection (glaucoma, diabetic retinopathy, and age-related macular degeneration) and systemic disease prediction (diabetes and hypertension) based on retinal imaging. We benchmarked four state-of-the-art FMs (RETFound, VisionFM, RetiZero, and DINORET) using standardized datasets from multiple countries and evaluated their performance using AUC and F1 metrics. Our results show that DINORET and RetiZero achieve superior performance in both ophthalmic and systemic disease tasks, with RetiZero exhibiting stronger generalization on external datasets. Regarding fusion strategies, the Gating-based approach provides modest improvements in predicting glaucoma, AMD, and hypertension. Despite these advances, predicting systemic diseases, especially hypertension in external cohort remains challenging. These findings provide an evidence-based evaluation of ophthalmic FMs, highlight the benefits of model fusion, and point to strategies for enhancing their clinical applicability.